Tissue Transglutaminase IgG (TTG-G)

Celiac disease, an autoimmune condition triggered by gluten, can cause symptoms such as diarrhea, abdominal pain, bloating, fatigue, weight loss, and nutritional deficiencies. Some individuals may also experience skin rashes, joint pain, or fertility problems. The TTG-IgG blood test detects antibodies produced in response to gluten, aiding in the diagnosis of celiac disease—especially in those with IgA deficiency. Diagnosis usually combines blood tests, genetic testing, and intestinal biopsy. Early detection and management are key to preventing complications and improving quality of life.